SIM2 anticorps (Middle Region)
Aperçu rapide pour SIM2 anticorps (Middle Region) (ABIN5517795)
Antigène
Voir toutes SIM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 92%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human SIM2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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Autre désignation
- SIM2
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Sujet
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM2, BHLHE15,
Protein Size: 667 -
ID gène
- 6493
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UniProt
- Q14190
Antigène
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